Publications

Presented below are the published projects in the group. Most of these are synthetic challenges presented to us by our close collaborators at Novartis, Takeda, Evonik, PHT International, Hovione, and Anthem Biosciences. We are also thrilled to be collaborating with the Bill & Melinda Gates Foundation, working on targets in the malaria, COVID-19, HIV, and tuberculosis (TB) areas. Several graduate students in the group have spent 3-6-months doing internships at Novartis in Basel, or in Cambridge, MA, working at Novartis and Takeda. Likewise, one student has interned at Evonik in Hanau, Germany, also helping to transfer technological advances to our industrial partners. There will surely be others from the group occupying such positions, as chemistry in water continues to advance, and to blossom.

This page is organized in three different sections: "Articles", "Reviews" and "Books". You can also access the full list by scrolling down this page. Your comments and suggestions are always welcome. 

Cover Pictures

 

Full list of publications

No.

Year Title and Authors Journal  
422 2024

The impact of earth-abundant metals as a replacement for Pd in cross coupling reactions

Luescher, M. U.; Gallou, F.; and Lipshutz, B. H.

submitted Perspective
421 2024
Synthesis of S,S-di(pyridin-2-yl)carbonodithioate (DPDTC) and its use in the reduction of a carboxylic acid to the corresponding alcohol, employing a green reaction medium.
 
Iyer, K. S.; Yirak, J. R.; Muchalski, H.; and Lipshutz, B. H.
submitted  
420 2024
Preparation of a key intermediate en route to the anti-HIV drug lenacapavir
 
Caravez, J. C.; Hu, Y.; Oftadeh, E.; Mamo, K. T.; and Lipshutz, B. H.
J. Org. Chem. accepted  
419 2024
Reducing the cost of making drugs for low/limited-income countries by going green

Lipshutz, B. H.

Trends in Chem.  Opinion
418 2024
Ligated Pd–catalyzed aminations of aryl/heteroaryl halides with aliphatic amines under sustainable aqueous micellar conditions
 
Iyer, K. S.‡; Kavthe, R. D.‡; Lammert Jr., R. M.; Yirak, J. R.; and Lipshutz, B. H.
JACS Au Article
417 2024
Nanoparticles as heterogeneous catalysts for ppm Pd–catalyzed aminations in water
 
Iyer, K. S.; Kavthe, R. D.; Hu, Y.; and Lipshutz, B. H.
ACS Sus. Chem. Eng. 12, 1997-2008 Article
416 2024

Palladium-Catalyzed Aminations in Flow... on Water

Wong, M. J.; Oftadeh, E.; Saunders, J. M.; Wood, A. B.; and Lipshutz, B. H.

ACS Catal. 14, 1545-1552 Article
415 2023

On the role of surfactants:  rethinking "aqueous” chemistry

Lipshutz, B. H.

Green Chem. 26, 739–752 Perspective
414 2023

Challenging cross couplings, in water, aided by in-situ iodination of (hetero)aromatic bromides

Thomas, R. M.; Obbard, D. B.; and Lipshutz, B. H. 

Chem. Sci. 14, 13503–13507 Article
413 2023
Use of Dipyridyldithiocarbonate (DPDTC) as an Environmentally Responsible Reagent Leading to Esters and Thioesters under Green Chemistry Conditions
 
Freiberg, K. M.; Ghiglietti, E.; Scurria, M.; and Lipshutz, B. H.
Green Chem. 25, 9941-9947

Article

Highlight

412 2023
Impact of Nonionic Surfactants on Reactions of IREDs. Applications to One-Pot Chemoenzymatic Sequences in Water
 
Li, X.; Hu, Y.; Bailey, J. D.; and Lipshutz, B. H.
Org. Lett.  Article
411 2023
Pd-catalyzed carbonylations of aryl/heteroaryl halides in aqueous micellar media
 
Caravez, J. C.; Wong, M. J.‡, Kavthe, R. D.‡, Takale, B. S.; and Lipshutz, B. H.
ACS Catal. 13, 12383−12390 Article
410 2023
Status check: Biocatalysis; it’s Use With & Without Chemocatalysis. How does the fine chemicals industry view this area?
 
Gallou, F.; Gröger, H.; and Lipshutz, B. H. 
Green Chem. 25, 6092

Review

Opinion

409 2023
A streamlined, green, and sustainable synthesis of the anticancer agent erdafitinib
 
Singhania, V.; Nelson, C. B.; Reamey, M.; Morin, E.; Kavthe, R. D.; and Lipshutz, B. H.
Org. Lett. 25, 4308-4312 Article
408 2023
A Sustainable, Efficient, and Potentially Cost-effective Approach to the Antimalarial Drug Candidate MMV688533
 
Kavthe, R. D.; Iyer, K. S.; Caravez, J. C.; and Lipshutz, B. H.

Chem. Sci. 14, 6399-6407

Article

Commentary

407 2023
On the Sustainability of Palladium in Organic Synthesis: A Perspective
 
Lipshutz, B. H. 
Johnson Matthey Technol. Rev. 67, 278–284 Perspective
406 2023

Facile, green, and functional group-tolerant reductions of carboxylic acids...in water

Iyer, K. S.; Nelson, C. B.; and Lipshutz, B. H.

Green Chem. 25, 2663-2671

Article

Highlight

Highlight

405 2023
A New Preparation of ppm Pd-Containing Nanoparticles as Catalysts for Chemistry in Water
 
Hu, Y.; Li, X.; Jin, G.; and Lipshutz, B. H.
ACS Catal. 13, 3179-3186 Article
404 2023
Direct formation of amide/peptide bonds from carboxylic acids:  no traditional coupling reagents, 1-pot, and green
 

Freiberg, K. M.; Kavthe, R. D.; Thomas, R. M.; Fialho, D. M.; Dee, P.; Scurria, M.; and Lipshutz, B. H.

Chem. Sci. 14, 3462-3469

Article

Highlight

403 2023

Introducing Savie:  A Biodegradable Surfactant Enabling Chemo- and Bio-catalysis & Related Reactions in Recyclable Water

Kincaid, J. R. A.; Wong, M. J.; Akporji, N.; Gallou, F.; Fialho, D. M.; Lipshutz, B. H.

 
J. Am. Chem. Soc. 145, 4266-4278

Article

Highlight

402 2023

Where chemocatalysis meets biocatalysis:  in water

Gröger, H.; Gallou, F.; Lipshutz, B. H.

Chem. Rev. 123, 5262–5296

Review

401 2022

A 1-pot synthesis of the SARS-CoV-2 Mpro inhibitor nirmatrelvir, the key ingredient in Paxlovid

Caravez, J. C.; Iyer, K. S.; Kavthe, R. D.; Kincaid, J. R. A.; and Lipshutz, B. H.

Org. Lett. 24, 9049 Article
400 2022

An Efficient & Sustainable Synthesis of the Antimalarial Drug Tafenoquine

Kavthe, R. D.; Kincaid, J. R. A.; Lipshutz, B. H.

ACS Sus. Chem. Eng. 10, 16896

Article
399 2022

Nanomicelle-enabled chemoenzymatic catalysis: Clean chemistry in “dirty” water

Lipshutz, B. H.

Chem Catalysis, 3, 1

Perspective

398 2022

A Sustainable Synthesis of the SARS-CoV-2 Mpro Inhibitor Nirmatrelvir, the Active Ingredient in Paxlovid

Kincaid, J. R. A.; Caravez, J. C.; Iyer, K. S.; Kavthe, R. D.; Fleck, N.; Aue, D. H.; Lipshutz, B. H.

Comm. Chem. 5, 156

Article

Highlight

397 2022

Nanoparticle-catalyzed Green Synthetic Chemistry... in Water

Lipshutz, B. H.; Caravez, J. C.; Iyer, K. S.

Curr. Opin. Green. Sus. Chem. 38, 100686 Review
396 2022

ppm Pd-Containing Nanoparticles as Catalysts for Negishi Couplings…in Water

Hu, Y.; Wong, M. J.; Lipshutz, B. H.

Angew. Chem. Int. Ed. 61, e202209784 Article
395 2022

An environmentally responsible route to tezacaftor, a drug for treatment of cystic fibrosis prepared in water via ppm Au catalysis as entry to 2-substituted indoles

Fleck, N.; Thomas, R. M.; Müller, M.; Grimme, S.; Lipshutz, B. H.

Green Chem. 24, 6517 Article
394 2022

Impact of Aqueous Micellar Media on Biocatalytic Transformations Involving Transaminase (ATA); Applications to Chemoenzymatic Catalysis

Dussart-Gautheret, J.; Yu, J.; Ganesh, K.; Rajendra, G.; Gallou, F.; Lipshutz, B. H.

Green Chem. 24, 6172

Article
393 2022

Allylations of Aryl/Heteroaryl Ketones: Neat, Clean, and Green. Applications to Targets in the Pharma- and Nutraceutical Industries

Li, X.; Wood, A.; Lee, N.; Gallou, F.; Lipshutz, B. H.

Green Chem. 24, 4909 Article
392 2022

An Environmentally Responsible and Cost-effective Synthesis of the Antimalarial Drug Pyronaridine 

Kincaid, J. R. A.; Kavthe, R., D.; Caravez, J. C.; Takale, B. S.; Thakore, R. R.; and Lipshutz, B. H.

Org. Lett. 24, 3342 Article
391 2022

An Environmentally Responsible Synthesis of the Antitumor Agent Lapatinib (Tykerb)

Yu, J.; Iyer, K. S.; Lipshutz, B. H.

Green Chem. 24, 3640 Article
390 2022

Dehydration of primary amides to nitriles in water. Late-stage functionalization and 1-pot multistep chemoenzymatic processes under micellar catalysis conditions

Wood, A. B.; Kincaid, J. R. A.; Lipshutz, B. H.

Green Chem. 24, 2853

Article
389 2022

Lipase-catalyzed esterification in water enabled by nanomicelles. Applications to 1-pot multi-step sequences

Singhania, V.; Cortes-Clerget, M.;Dussart-Gautheret, J.; Akkachairin, B.; Yu, J.; Akporji, N; Gallou, G; Lipshutz, B. H.

Chem. Sci. 13, 1440 Article
388 2021

High Turnover Pd/C Catalyst for Nitro Group Reductions in Water. One-Pot Sequences and Syntheses of Pharmaceutical Intermediates

Li, X.; Thakore, R. R.; Takale, B. S.; Gallou, F.; Lipshutz, B. H.

Org. Lett. 23, 8114 Article
387 2021

Bisulfite addition compounds as educts for reductive aminations in water

Li, X.; Iyer, K.S.; Thakore, R. R.; Bailey, J. D.; Leahy, D. K.; Lipshutz, B. H.

Org. Lett. 23, 7205

Article
386 2021

Continuous Slurry Plug Flow Fe/ppm Pd Nanoparticle-Catalyzed Suzuki-Miyaura Couplings in Water Utilizing Novel Solids Handling Equipment

Wood, A. B., Plummer, S., Robinson, R. I., Smith, M., Chang, J., Gallou, F., Lipshutz, B. H.

Green Chem. 23, 7724

Article

Highlight

385 2021

Nanomicelle-enhanced, asymmetric ERED-catalyzed reductions of activated olefins. Applications to 1-pot chemo- and bio-catalysis sequences in water

Akporji, N., Singhania, V., Dussart-Gautheret, J., Gallou, F., Lipshutz, B. H.

Chem. Comm. 57, 11847 Article
384 2021

α-Arylation of (hetero)aryl ketones in aqueous surfactant media

Wood A. B., Roa, D. E, Gallou, F., Lipshutz, B. H.

Green Chem. 23, 4858 Article
383 2021

Copper-Catalyzed Asymmetric Reductions of Aryl/Heteroaryl Ketones under Mild Aqueous Micellar Conditions

Fialho, D. M., Etemadi-Davan, E., Langner, O. C., Takale, B. S., Gadakh, A., Sambasivam, G., Lipshutz, B. H.

Org. Lett. 23, 3282 Article
382 2021

Sustainable routes to amines in recyclable water using ppm Pd catalysis

Thakore, R. R., Iyer, K. S., Lipshutz, B. H.

Curr. Opin. Green. Sus. Chem. 31, 100493 Review
381 2021

Illuminating a path for organic synthesis towards sustainability. No one said it would be easy...

Lipshutz, B. H.

Synlett, 32, 1588 (Invited) Review
380 2021

“TPG-lite”: a new, simplified “designer” surfactant for general use in synthesis under micellar catalysis conditions in recyclable water 

Thakore, R. R., Takale, B. S., Hu, Y., Kostal, J., Gallou, F., Lipshutz, B. H.

Tetrahedron, 87, 132090 Article
379 2021

Water as the reaction medium in organic chemistry: from our worst enemy to our best friend"

Cortes-Clerget, M., Yu, J., Kincaid, J. R. A., Walde, P., Gallou, F., Lipshutz, B. H.

Chem. Sci. 12, 4237 Review
378 2021

Water-Sculpting of a Heterogeneous Nanoparticle Pre-catalyst for Mizoroki-Heck Couplings Under Aqueous Micellar Catalysis Conditions

Pang, H., Hu, Y., Yu, J., Gallou, F., Lipshutz, B. H.

J. Am. Chem. Soc. 143, 3373 Article
377 2021

Late-stage Pd-catalyzed cyanations of aryl/heteroaryl halides in aqueous micellar media

Thakore, R. R., Takale, B. S., Singhania, V., Gallou, F., Lipshutz, B. H. 

ChemCatChem. 13, 212

Article
376 2020

"Mild and robust Stille reactions in water using ppm levels of a new triphenylphosphine-based palladacycle"

Takale, B. S., Thakore, R. R., Casotti, G., Li, X., Gallou, F., Lipshutz, B. H. 

Angew. Chem. Int. Ed. 60, 4158

Hot Article

Article
375 2020

Safe, Scalable, Inexpensive, and Mild Nickel‐Catalyzed Migita‐like C–S Cross‐Couplings in Recyclable Water

Yu, T., Pang, H., Cao, Y., Gallou, F., Lipshutz, B. H. 

Angew. Chem. Int.  Ed. 60, 3708 Article
374 2020

Environmentally responsible, safe, and chemoselective catalytic hydrogenation of olefins: ppm level Pd catalysis in recyclable water at room temperature

Takale, B. S., Thakore, R. R., Gao, E. S., Gallou, F. Lipshutz, B. H.

Green Chem. 22, 6055

Hot Article

Article
373 2020

1-Pot synthesis of indoles and pyrazoles via Pd-catalyzed couplings/cyclizations enabled by aqueous micellar catalysis

Landstrom, E., Akporji, N., Gabriel, C. M., Lee, N. R., Braga, F. C., Lipshutz, B. H. 

Org. Lett.22, 6543 Article
372 2020

Endangered Palladium — Palladacycles at the ppm level to the rescue

Moghadam, F., Langner, O., Lipshutz, B. H. 

Chemistry Today Review
371 2020

Chemoselective Reductive Aminations in Aqueous Nanoreactors Using Parts per Million Level Pd/C Catalysis

Thakore, R. R., Takale, B. S., Casotti, G., Gao, E. S., Jin, H. S., Lipshutz, B. H. 

Org. Lett. 22, 6324 Article
370 2020

Sustainable Palladium-Catalyzed Tsuji−Trost Reactions Enabled by Aqueous Micellar Catalysis

Lee, N. R., Moghadam, F. A., Braga, F. C., Lippincott, D. J., Zhu, B., Gallou, F., Lipshutz, B. H. 

Org. Lett., 22, 4949 Article
369 2020

Nickel Nanoparticle-Catalyzed Mono- and Di-Reductions of gem-Dibromocyclopropanes Under Mild, Aqueous Micellar Conditions

Wood, A. B., Cortes-Clerget, M., Kincaid, J. R. A., Akkachairin, B., Singhania, V., Gallou, F., Lipshutz, B. H. 

Angew. Chem. Int. Ed. 59, 17587 Article
368 2020

Sustainable and Cost-Effective Suzuki–Miyaura Couplings toward the Key Biaryl Subunits of Arylex and Rinskor Active

Takale, B. S., Thakore, R. R., Irvine, M. N., Schuitman, A., Li, X., Lipshutz, B. H.

 Org. Lett. 12, 4823 Article
367 2020

Continuous Flow Suzuki-Miyaura Couplings in Water Under Micellar Conditions in a CSTR Cascade Catalyzed by Fe/ppm Pd Nanoparticles

Wood, A. B., Nadiwale, K. Y., Mo, Y., Jin. B., Pomberger, A., Schultz, V. L., Gallou, F., Jensen, K. F., Lipshutz, B. H. 

Green Chem. 22, 3441  Article 
366 2020

N2Phos – an easily made, highly effective ligand designed for ppm level Pd-catalyzed Suzuki–Miyaura cross couplings in water

Akporji, N., Thakore, R. R., Cortes-Clerget, M., Anderson, J., Landstrom, E., Aue, D. H., Gallou, F., Lipshutz, B. H. 

Chem. Sci. 11, 5205  Article
365 2020

Earth-Abundant and Precious Metal Nanoparticle Catalysis

Cortes-Clerget M., Akporji N., Takale, B. S., Wood, A., Landstrom E., Lipshutz, B. H. 

Topics in Organometallic Chemistry  Book
364 2020

Recent advances in Cu-catalyzed C(sp3)-Si and C(sp3)-B bond formation

Takale, B. S., Thakore, R. R., Etemadi-Davan, E., Lipshutz, B. H. 

Beilstein J. Org. Chem. 16, 691 Review 
363 2019

Surfactant Technology: With New Rules, Designing New Sequences Is Required!

Lippincott, D., Landstrom, E., Cortes-Clerget, M., Lipshutz, B. H., Buescher, K., Schreiber, R., Durano, C., Parmentier, M., Ye, N., Shi, M., Yang, H., Andersson, M., Gallou, F.

Org. Process Res. Dev. 24, 841 Article
362 2019

A sustainable 1-pot, 3-step synthesis of boscalid using ppm level Pd catalysis in water

Takale, B. S., Thakore, R. R., Mallarapu, R., Gallou, F., Lipshutz, B. H.

Org. Process Res. Dev. 24, 101 Article
361 2019

An environmentally responsible 3-pot, 5-stepsynthesis of the antitumor agent sonidegib using ppm levels of Pd catalysis in water

Takale, B. S., Thakore, R. R., Kong, F. Y., Lipshutz, B. H.

Green Chem. 21, 6258 Article
360 2019

N,C-Disubstituted Biarylpalladacycles as Pre-catalysts for ppm Pd-catalyzed Cross Couplings in Water Under Mild Conditions

Thakore, R. R., Takale, B. S., Gallou, F., Reilly, J., Lipshutz, B. H.

ACS Catal. 12, 11647  Article 
359 2019

Fe-catalyzed reductive couplings of terminal (hetero)aryl alkenes and alkyl halides under aqueous micellar conditions

Pang, H., Wang, Y., Gallou, F., Lipshutz, B. H. 

J. Am. Chem. Soc. 141, 17117 Article
358 2019

Discovery-Based SNAr Experiment in Water Using Micellar Catalysis

Landstrom, E. B., Nichol, M., Lipshutz, B. H., Gainer, M. J.

J. Chem. Educ. 11, 2668 Article
357 2019

Sustainable ppm Level Palladium-Catalyzed Aminations in Nanoreactors Under Mild, Aqueous Conditions

Zhang, Y., Takale, B. S., Gallou, F., Reilly, J., Lipshutz, B. H. 

Chem. Sci. 10, 10556 Article
356 2019

"Selective Deprotection of the Diphenylmethylsilyl (DPMS) Hydroxyl Protecting Group Under Environmentally Responsible, Aqueous Conditions"

Akporji, N., Lieberman, J., Maser, M., Yoshimura, M., Boskovic, Z., Lipshutz, B. H. 

Chem. Cat. Chem. 11, 5743 Article
355 2019

Synergistic Effects of ppm Levels of Palladium on Natural Clinochlore: a New Reagent for Reductions of Nitroarenes

Gholinejad, M., Oftadeh, E., Shojafar, M., Sansano, J. M., and

Lipshutz, B. H. 

Chem. Sus. Chem. 12, 4240 Article
354 2019

Atroposelective Total Synthesis of the Fourfold ortho-Substituted Naphthyltetrahydroisoquinoline Biaryl O,N-Dimethylhamatine

Slack, E. D., Seupel, R., Aue, D. H., Bringmann, G., and Lipshutz, B. H.

Chem. Eur. J. 25, 14237 Article
353 2019

A new, substituted palladacycle for ppm level Pd-catalyzed Suzuki-Miyaura cross couplings in water

Takale, B. S., Thakore, R. R., Handa, S., Gallou, F., Reilly, J. and Lipshutz, B. H.

Chem. Sci. 10, 8825 Article
352 2019

MC-1. A “designer” surfactant engineered for peptide synthesis in water at room temperature

Cortes-Clerget, M., Spink, S. E., Gallagher, G. P., Chaisemartin, L., Filaire, E., Berthon, J-Y., and Lipshutz, B. H.

Green Chem. 21, 2610 Article
351 2019

"Organometallic Processes in Water" in "Topics in Organometallic Chemistry"

Gallou, F., Lipshutz, B. H. 

Topics in Organometallic Chemistry Chapter
350 2019

Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis

Cortes-Clerget, M.; Akporji, N.; Zhou, J.; Gao, F.; Guo, P.; Parmentier, M.; Gallou, F.; Berthon, J-Y.; Lipshutz, B. H.

Nat. Comm. 10, 2169

Article

Behind the paper

Highlight

348 2019

Synthetic chemistry in water: applications to peptide synthesis and nitro-group reductions

Cortes-Clerget, M.; Lee, N. R.; Lipshutz, B. H.

Nat. Protoc. 14, 1108 Article
347 2019

Coolade. A Low-Foaming Surfactant for Organic Synthesis in Water

Lee, N. R.; Cortes-Clerget, M.; Wood, A.;  Lippincott, D. J.; Pang, H.; Moghadam, F.; Gallou, F.; Lipshutz, B. H.

ChemSusChem. 12, 3159 Article
346 2019

Sonogashira Couplings Catalyzed by Fe Nanoparticles Containing ppm Levels of Reusable Pd, under Mild Aqueous Micellar Conditions

Handa, S.; Bo, J.; Bora, P. P.; Wang, Y.; Zhang, X.; Gallou, F.; Reilly, J.; Lipshutz, B. H.

ACS Catal. 9, 3, 2423 Article
345 2019

ppm Pd-Catalyzed, Cu-free Sonogashira couplings in water using commercially available catalyst precursors

Bo, J.; Reilly, J.; Gallou, F.; Lipshutz, B. H.

Chem. Sci. 10, 3481

Highlighted in ChemSci Pick of the Week

Article

Highlight

344 2018

Copper-Catalyzed Oxidative Cleavage of Electron-Rich Olefins in Water at Room Temperature

Lippincott, D. J.; Trejo-Soto, P. J.; Gallou, F.; Lipshutz, B. H.

Org. Lett., 20, 5094. Article
343 2018

Synthesis of Functionalized 1,3-Butadienes via Pd-Catalyzed Cross-Couplings of Substituted Allenic Esters in Water at Room Temperature

Lippincott, D. J.; Linstadt, R. T. H.; Maser, M. R.; Gallou, F.; Lipshutz, B. H.

Org. Lett., 20, 4719.

Article
342 2018

EvanPhos. A New Ligand for ppm Pd-Catalyzed Suzuki-Miyaura Coupling in Either Organic Solvent or Water

Landstrom, E. B.; Handa, S.; Aue, D. H.; Gallou, F.; Lipshutz, B. H.

Green Chem. 20, 3436

Article
341 2018

Catalyst: Imagine Doing Chemistry At No Cost... To The Environment 

Lipshutz, B. H.

Chem, 4, 2004 Opinion
340 2018

B-Alkyl sp3-sp2 Suzuki-Miyaura Couplings Under Mild Aqueous Micellar Conditions

Lee, N. R.; Linstadt, R. T. H.; Gloisten, D. J.; Gallou, F.;  Lipshutz, B. H.

Org. Lett. 20, 2902 Article
339 2018

Structure of Nanoparticles Derived from Designer Surfactant TPGS-750-M in Water, as Used in Organic Synthesis

Andersson, M.; Gallou, F.; Klumphu, P.; Takale, B.,  Lipshutz, B. H.

Chem. Eur. J. 24, 6778

Article
338 2018

PQS-enabled Visible-Light Iridium Photoredox Catalysis in Water at Room Temperature

Bu, M-j.; Cai, C.; Gallou, F.; Lipshutz, B. H.

Green Chem. 20, 1233 Article
337 2018

The Hydrophobic Effect Applied to Organic Synthesis: Recent Synthetic Chemistry "in Water"

Lipshutz, B. H.; Ghorai, S.; Cortes-Clerget, M.

Chem. Eur. J. 24, 6672

Review

Frontispiece

336 2018

Sustainable HandaPhos-ppm Palladium Technology for Copper-Free Sonogashira Couplings in Water under Mild Conditions

Handa, S.; Smith, J. D.; Zhang, Y.; Takale, B. S.; Gallou, F.; Lipshutz, B. H.

Org. Lett. 20, 542 Article
335 2018

Synthetic Chemistry in a Water World. New Rules Ripe for Discovery

Lipshutz, B. H.

Curr. Opin. Green Sustain. Chem. 11, 1 Review
334 2018

Synergistic Effects in Fe Nanoparticles doped with ppm levels of (Pd + Ni). A New Catalyst for Sustainable Nitro Group Reductions

Pang, H.; Gallou, F.; Sohn, H.; Camacho-Bunquin, J.; Delferro, M.; Lipshutz, B. H.

Green Chem. 20, 130 Article
333 2017

Carbonyl Iron Powder: A Reagent for Nitro Group Reduction Under Aqueous Micellar Catalysis Conditions

Lee, N. R.; Bikovtseva, A. A.; Cortes-Clerget, M.; Gallou, F.; Lipshutz, B. H.

Org. Lett. 19, 6518 Article
332 2017

A Micellar Catalysis Strategy for Suzuki-Miyaura Cross-Coupling of 2-Pyridyl MIDA Boronates: No Copper, in Water, Very Mild Conditions

Isley, N. A.; Wang, Y.; Gallou, F.; Handa, S.; Aue, D. H.; Lipshutz, B. H.

ASC Catal., 7, 8331 Article
331 2017

The ‘Nano-to-Nano’ Effect Applied to Organic Synthesis in Water

Lipshutz, B. H.

Johnson Matthey Technol. Rev., 61, 196 Article
330 2017

Tandem deprotection/coupling for peptide synthesis in water at room temperature

Cortes-Clerget, M.; Berthon, J-Y.; Krolikewicz-Renimel, I.; Chaisemartin, L.; Lipshutz, B. H.

Green Chem., 19, 4263 Article
329 2017

Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature

Klumphu, P.; Desfeux, C.; Zhang, Y.; Handa, S.; Gallou, F.; Lipshutz, B. H.

Chem. Sci., 8, 6354

Article
328 2017

Fe/ppm Cu nanoparticles as a recyclable catalyst for click reactions in water at room temperature

Adenot, A.; Landstrom, E. B.; Gallou, F.; Lipshutz, B. H.

Green Chem., 19, 2506 Article
327 2017

When Does Organic Chemistry Follow Nature’s Lead and “Make the Switch”?

Lipshutz, B. H.

J. Org. Chem., 82, 2806 (Invited) Article

326

2017

Sustainable and Scalable Fe/ppm Pd Nanoparticle Nitro Group Reductions in Water at Room Temperature

Gabriel, C. M.; Parmentier, M.; Riegert, C.; Lanz, M.; Handa, S.; Lipshutz, B. H.; Gallou, F.

OPRD, 21, 247 Article
325 2017

Control of Chemo-, Regio-, and Enantioselectivity in Copper Hydride Reductions of Morita-Baylis-Hillman Adducts

Linstadt, R. T. H; Peterson, C. A.; Jette, C. I.; Boskovic, Z. V.; Lipshutz, B. H.

Org. Lett., 19, 328 Article
324 2017

From Milligrams to Grams. SNAr Reactions in Aqueous Nanomicelles: No Dipolar Aprotic Solvents Needed

Lee, N. R.; Gallou, F.; Lipshutz, B. H.

OPRD, 21, 218 Article
323 2017

Effects of Co-solvents on Reactions Run under Micellar Catalysis Conditions

Gabriel, C. M.; Lee, N. R.; Bigorne, F.; Klumphu, P.; Parmentier, M.; Gallou, F.; Lipshutz, B. H.

Org. Lett., 19, 194 Article
322 2017

Synthesis of Functionalized [3], [4], [5] and [6]Dendralenes through Palladium-Catalyzed Cross-Couplings of Substituted Allenoates

Lippincott, D. J.; Linstadt, R. T. H.; Maser, M. R.; Lipshutz, B. H.
 

Angew. Chem., Int. Ed. 56, 847.

Angew. Chem. 129, 865.

Article
321 2016

Synergistic and Selective Copper/ppm Pd-Catalyzed Suzuki-Miyaura Couplings: In Water, Mild Conditions, with Recycling

Handa, S.; Smith, J. D.; Hageman, M. S.; Gonzalez, M.; Lipshutz, B. H.
 
ACS Catal., 6, 8179 Article
320 2016

The Evolution of Solvents in Organic Chemistry

Lipshutz, B. H.; Gallou, F.; Handa, S.
 
ACS Sustainable Chem. Eng., 4, 5838 (Invited) Article
319 2016

Safe and Selective Nitro Group Reductions Catalyzed by Sustainable and Recyclable Fe/ppm Pd Nanoparticles in Water at Room Temperature

Feng, J.; Handa, S.; Gallou, F.; Lipshutz, B. H.
 
Angew. Chem. Int. Ed., 55, 8979 Article
318 2016

Cationic Pd(II)-catalyzed C–H activation/cross-coupling reactions at room temperature: synthetic and mechanistic studies

Nishikata, T.; Abela, A. R.; Huang, S.; Lipshutz, B. H.
 
Beilstein J. Org. Chem, 12, 1040 Article
317 2016

HandaPhos: A General Ligand Enabling Sustainable ppm Levels of Palladium-catalyzed Cross-Couplings in Water at Room Temperature

Handa, S.; Andersson, M. P.; Gallou, F.; Reilly, J.; Lipshutz, B. H.
 
Angew. Chem. Int. Ed., 55, 4914 Article
316 2015

High-performance mussel-inspired adhesives of reduced complexity

Ahn, B. K.; Das, S.; Linstadt, R. T. H. ;Kaufman, Y.; Martinez-Rodriguez, N. R; Mirshafian, R.; Kesselman, R.; Talmon, Y.; Lipshutz, B. H.; Israelachvili, J. N.; Waite, J. H.
 
Nat. Comm., 6, 8663 Article
315 2015

Sustainable Fe-ppm Pd nanoparticle catalysis of Suzuki-Miyaura cross-couplings in water

Handa, S.; Wang, Ye; Gallou, F.; Lipshutz, B. H.

Science, 349, 1087

Abstract

Article

314 2015

Nucleophilic Aromatic Substitution Reactions in Water Enabled by Micellar Catalysis

Isley, N. A.; Linstadt, R. T. H.; Kelly, S. M.; Gallou, F.; Lipshutz, B. H.

Org. Lett., 17, 4734

(Outstanding Publication of the Year)

Article

Review

313 2015

Nanonickel-Catalyzed Suzuki–Miyaura Cross-Couplings in Water

Handa, S.; Slack, E. D.; Lipshutz, B. H.

Angew. Chem. Int. Ed., 54 ,11994 Article
312 2015

Kumada–Grignard-type biaryl couplings on water

Bhattacharjya, A.; Klumphu, P.; Lipshutz B. H.

Nat. Comm., 6, 7401 Article
311 2015

Amide and Peptide Bond Formation in Water at Room Temperature

Gabriel, C. M.; Keener, M.; Gallou, F.; Lipshutz, B. H.

Org. Lett., 17, 3968 Article
310 2015

Reductions of Aryl Bromides in Water at Room Temperature

Fennewald, J. C.; Landstrom, E. B.; Lipshutz, B. H.

Tet. Lett., 56, 3608 Article
309 2015

Ligand-?Free, Palladium-?Catalyzed Dihydrogen Generation from TMDS: Dehalogenation of Aryl Halides on Water

Bhattacharjya, A.; Klumphu, P.; Lipshutz, B. H.

Org. Lett., 17, 1122 Article
308 2015

Dehalogenation of Functionalized Alkyl Halides in Water at Room Temperature

N. A. Isley, M. S. Hageman, B. H. Lipshutz

Green Chem., 2015, 17, 893

Article
307 2014

Transitioning Organic Synthesis from Organic Solvents to Water. What's Your E Factor?

B. H. Lipshutz, S. Ghorai

Green Chem., 16, 3660

Article

Cover

306 2014

Asymmetric Gold-Catalyzed Lactonizations in Water at Room Temperature

S. Handa, D. J. Lippincott, D. H. Aue, B. H. Lipshutz

Angew. Chem., Int. Ed., 53, 10658 Article
305 2014

A Palladium Nanoparticle-Nanomicelle Combination for the Stereoselective Semihydrogenation of Alkynes in Water at Room Temperature

E. D. Slack, C. M. Gabriel, B. H. Lipshutz

Angew. Chem., Int. Ed., 53, 14051 Article
304 2014

Stereoretentive Pd-Catalyzed Kumada-Corriu Couplings of Alkenyl Halides at Room Temperature 

A. Krasovskiy; S. Haley, K. Voidtritter, B. H. Lipshutz

Org. Lett. 16, 4066 Article

303

2014

CuH in Asymmetric Reductions, In Copper-Catalyzed Asymmetric Synthesis

B. H. Lipshutz

Wiley-VCH

Review

Chapter

302 2014

Transitioning organic synthesis from organic solvents to water. What’s your E Factor?

B. H. Lipshutz, S. Ghorai

Green Chem., 16, 3660 Article
301 2014

Copper-catalyzed Hydrophosphinations in Water at Room Temperature

N. A. Isley, R. T. Linstadt, E. Slack, B. H. Lipshutz

Dalton Trans., 43, 13196 Article
300 2014

Aerobic Oxidation in nanomicelles of Aryl Alkynes, in Water at Room Temperature

S. Handa, J. C. Fennewald, B. H. Lipshutz

Angew. Chem., Int. Ed., 53, 3432  Article
299 2014

Stereoselective Silylcuprations of Conjugated Alkynes in Water at Room Temperature

R. T. H. Linstadt, C. A. Peterson, D. J. Lippincott, C. I. Jette, B. H. Lipshutz

Angew. Chem. Int. Ed., 53, 4159 Article
298 2014

Selective oxidations of activated alcohols in water at room temperature

B. H. Lipshutz, M. Hageman, J. C. Fennewald, R. Linstadt, E. Slack, K. Voigtritter

Chem. Comm. 50, 11378

Article

297 2014

Leveraging the Micellar Effect:  Gold-Catalyzed Dehydrative Cyclizations…in Water at Room Temperature

S. R. K. Minkler, N. A. Isley, D. J. Lippincott, N. Krause, B. H. Lipshutz

Org. Lett., 16, 724 Article
296 2014

Copper-catalyzed trifluoromethylation of N-arylacrylamides “on water” at Room Temperature 

F. Yang, P. Klumphu, Y-M. Liang, B. H. Lipshutz

Chem. Comm., 50, 936 Article
295 2014

“Nok”: A Phytosterol-Based Amphiphile Enabling Transition Metal-Catalyzed Couplings in Water at Room Temperature 

P. Klumphu, B. H. Lipshutz

J. Org. Chem., 79, 888         Article
294 2014

Chemoselective Reductions of Nitroaromatics in Water at Room Temperature

S. M. Kelly, B. H. Lipshutz

Organic Lett., 16, 98 Article
293 2014

Installation of Protected Ammonia Equivalents onto Aromatic and Heteroaromatic Rings in Water Enabled by Micellar Catalysis

N. A. Isley, S. Dobarco, B. H. Lipshutz

Green Chem., 16, 1480 Article
292 2014

Trifluoromethylations of Heterocycles in Water at Room Temperature

J. C. Fennewald, B. H. Lipshutz

Green Chem., 16, 1097 Article
291 2013

Transforming Suzuki-Miyaura cross-couplings of MIDA boronates into a green technology: No Organic Solvents

N. A. Isley, F. Gallou, B. H. Lipshutz

J. Am. Chem. Soc., 135, 17707 Article
290 2013

Applying the Hydrophobic Effect to Transition Metal-Catalyzed Couplings in Water at Room Temperature, In Transition Metal-Catalyzed Couplings in Process Chemistry

B. H. Lipshutz

Wiley-VCH

Review

Chapter

289 2013

“Click” and Olefin Metathesis Chemistry in Water at Room Temperature Enabled by Biodegradable Micelles

B. H. Lipshutz, Z. Boskovic, C. S. Crowe, V. K. Davis, H. C. Whittemore, D. A. Vosburg, and A. G. Wenzel

 J. Chem. Ed.,  90, 1514          Article
288 2013

On the Way Towards Greener Transition Metal Catalyzed Processes as Quantified by E Factors

B. H. Lipshutz, N. A. Isley, J. C. Fennewald, E. D. Slack

Angew. Chem. Int. Ed. 52, 10911 Mini Review
287 2013

Organocopper Chemistry, in Organometallics in Synthesis, Fourth Manual

B. H. Lipshutz

Wiley-VCH Review
286 2013

Stille Couplings in Water at Room Temperature

G-P. Lu, C. Cai, B. H. Lipshutz

Green Chem., 15, 105 Article
285 2012
C–C Bond Formation via Copper-Catalyzed Conjugate Addition Reactions to Enones in Water at Room Temperature
 
B. H. Lipshutz, S. Huang, W. W. Y. Leong, G. Zhong, N. A. Isley
J. Am. Chem. Soc., 134, 19985 Article
284 2012

Ligand Effects on the Stereochemistry of Stille Couplings, as Manifested in Reactions of Z-Alkenyl Halides

G-P. Lu, K. R. Voigtritter, C. Cai, B. H. Lipshutz

Chem. Comm., 48, 8661 Article
283 2012

Ligand Effects on the Stereochemistry of Suzuki-Miyaura Couplings

G-P. Lu, K. R. Voigtritter, C. Cai, B. H. Lipshutz

J. Org. Chem. 77, 3700 Article
282 2012

Rh-Catalyzed Asymmetric 1,4-Addition Reactions in Water at Room Temperature with In-Flask Catalyst Recycling

B. H. Lipshutz, N. Isley, R. Moser, H. Leuser, B. R. Taft

Adv. Syn. Catal. 354, 3175 Article
281 2012

Modified Routes to the “Designer” Surfactant PQS

R. Moser, S. Ghorai, B. H. Lipshutz

J. Org. Chem. 77, 3143 Article
280 2012

Organocatalysis in Water at Room Temperature with In-Flask Catalyst Recycling

B. H. Lipshutz, S. Ghorai

Organic Lett. 14, 422 Article
279 2012

Palladium Catalysts in the Service of Green Chemistry

B. H. Lipshutz, B. R. Taft, A. R. Abela, S. Ghorai, A. Krasovskiy, C. Duplais

Platinum Chem. Rev., 56,  62 Review
278 2012

Designer Surfactant-Enabled Cross-Couplings in Water @ RT

B. H. Lipshutz and S. Ghorai

Aldrichimica Acta (invited), 45, 3 Review
277 2012

Regioselective reductions of b,b-disubstituted enones catalyzed by nonracemically ligated copper hydride

K. Voigtritter, N. Isley, R. Moser, D. H. Aue, B. H. Lipshutz

Tetrahedron Symposiun-in-Print (invited), 68, 3410 Article
276 2011

Gold Catalysis in Micellar Systems 

S. R. K. Minkler, B. H. Lipshutz, N. Krause

Angew. Chem., Int. Ed. 50, 7820 Article
275 2011

Organozinc Chemistry Under Micellar Catalysis Conditions.  Cross-Couplings Between Alkyl and Aryl Bromides in Water at Room Temperature

C. Duplais, A. Krasovskiy, and B. H. Lipshutz

Organometallics (invited), 30, 6090. Article
274 2011

Manipulating Micellar Environments for Enhancing Transition Metal-Catalyzed Cross-Couplings in Water at Room Temperature

B. H. Lipshutz, S. Ghorai, W. W. Y. Leong, R. Moser, B. R. Taft

J. Org. Chem. 76, 5061. Article
273 2011

Stereoselective Reactions Between Unbiased Alkenyl & Alkylzinc Halides:  Negishi-Plus Couplings 

A. Krasovskiy and B. H. Lipshutz

Organic Lett., 13, 3822. Article
272 2011

Ligand Effects in Negishi Cross-Couplings of Z-Alkenyl Halides

A. Krasovskiy, C. Duplais, B. H. Lipshutz

Org. Lett. 13, 3818. Article
271 2011

Enhanced Olefin Cross Metathesis Reactions:  The Copper Iodide Effect

K. Voigtritter, S. Ghorai, B. H. Lipshutz

J. Org. Chem. 76, 4697. Article
270 2011

TPGS-750-M:  A Second-Generation Amphiphile for Metal-Catalyzed Cross-Couplings in Watrer at Room Temperature

B. H. Lipshutz, S. Ghorai, A. R. Abela, R. Moser, T. Nishikata, C.Duplais, A. Krasovskiy

J. Org. Chem. 76, 4379. Article
269 2011

“On water” sp3-sp2- cross-couplings between benzylic and alkenyl halides

V. Krasovskaya, A. Krasovskiy, A. Bhattacharjya, B. H. Lipshutz

Chem. Comm. 47, 5717. Article
268 2011

Cross-couplings of alkyl halides with heteroaromatic halides, in water at room temperature

A. Krasovskiy, I. Thome, J. Graff, V. Krasovskaya, P. Konopelski, C. Duplais, B. H. Lipshutz

Tetrahedron Lett. 52, 2203. Article
267 2010

Stereoselective Negishi-like Couplings of Alkenyl Halides with Alkyl Halides in Water at Room Temperature

A. Krasovskiy, C. Duplais, B. H. Lipshutz

Org. Lett. 12, 4742. Article
266 2010

Miyaura Borylations of Aryl Bromides in Water @ RT

B. H. Lipshutz, R. Moser, K. R. Voigtritter

Isr. J. Chem. (invited) 50, 691. Article
265 2010

Asymmetric CuH-Catalyzed 1,4-Reductions in Water @ RT

S. Huang, K. Voigtritter, J. B. Unger, B. H. Lipshutz

Synlett Cluster on Green Chemistry (invited) 2041 Article
264 2010

Sustainability.  Getting Organic Solvents Out of Organic Reactions

R. Moser, S. Huang, A. Abela, B. H. Lipshutz

Chemistry Today (invited) 28, 50. Review
263 2010

Enantioselective Total Synthesis of Korupensamine B

S. Huang, T. Petersen, B. H. Lipshutz

J. Am. Chem. Soc. 132, 14021. Article
262 2010

Greening Up Cross-Coupling Chemistry

A. Abela, Z. Boskovic, T. Nishikata, C. Duplais, A. Krasovsky, B. H. Lipshutz

Topics in Catalysis 53, 985. Review
261 2010

CuH-Catalyzed Enantioselective 1,2-Reductions of a,b-Unsaturated Ketones

R. Moser, Z. V. Boskovic, C. S. Crowe, B. H. Lipshutz

J. Am. Chem. Soc. 132, 7852. Article
260 2010

Cationic Pd(II) Catalyzed Fujiwara-Moritani Reactions at Room Temperature in Water

T. Nishikata, B. H. Lipshutz

Org. Lett. 12, 1972. Article
259 2010

Cationic Pd(II) Catalysis:  C-H Activation/Suzuki-Miyaura Couplings at Room Temperature

T. Nishikata, A. R. Abela, S. Huang, B. H. Lipshutz

J. Am. Chem. Soc. 132, 4978. Article
258 2010

Cross-Couplings Between Benzylic and Aryl Halides “On Water.”  Synthesis of Diarylmethanes

C. Duplais, A. Krasovskiy, A. Wattenberg, B. H. Lipshutz

Chem. Comm. 46, 562 Article
257 2010

Room Temperature C-H Activation & Cross-Coupling of Aryl Ureas in Water

T. Nishikata, A. R. Abela, B. H.  Lipshutz

Angew. Chem. Int. Ed. 49, 781 Article
256 2010

UC Pd: A new form of Pd/C for Sonogashira couplings

C. Duplais, A. J. Forman, B. A. Baker, B. H. Lipshutz

Chem. Eur. J. 16, 3366 Article
255 2010

PQS-2.  Ring-closing and cross-metathesis reactions on lipophilic substrates: in water only at room temperature, with in-flask catalyst recycling

B. H. Lipshutz, S. Ghorai

Tetrahedron, 66,1057 (Symposium-in-Print; green chemistry; co-Editor) Article
254 2010

Pd-Catalyzed Synthesis of Allylic Silanes from Allylic Ethers

R. Moser, T. Nishikata, B. H. Lipshutz

Org. Lett. 12, 28 Article
253 2009

Synthesis and Characterization of Isomeric Vinyl-1,2,3-triazole Materials by Azide-Alkyne Click Chemistry

Nulwala, H.; Takizawa, K; Odukale, A.; Khan, A.; Thibault, R. J.; Taft, B. R.; Lipshutz, B. H.; Hawker, C. J.

Macromolecules 42, 6068. Article
252 2009

Cu/C-Catalyzed, Tandem 1-Pot Diazo Transfer-Click Reactions

C-T. Lee, S. Huang, and B. H. Lipshutz

Adv. Syn. Catal. 353, 3139 Article
251 2009

Asymmetric Conjugate Reductions of Coumarins.  A New Route to Tolterodine and Related Coumarin Derivatives

B. D. Gallagher, B. R. Taft, B. H. Lipshutz

Org. Lett. 11, 5374. Article
250 2009

Aminations of Allylic Phenyl Ethers via Micellar Catalysis at Room Temperature in Water

T. Nishikata, B. H. Lipshutz

Chem. Comm. 6472 Article
249 2009

Zinc-Mediated, Pd-Catalyzed Cross-Couplings in Water at Room Temperature without Prior Formation of Organozinc Reagents

A. Krasovskiy, C. Duplais, B. H. Lipshutz

J. Am. Chem. Soc. 131, 15592 Article
248 2009

An (NHC)CuH-Catalyzed Entry to Allenes via Propargylic Carbonate SN2’ Reductions

C. Deutsch, B. H. Lipshutz, N. Krause

Org. Lett. 11, 5010. Article
247 2009

Allylic Ethers as Educts for Suzuki-Miyaura Couplings in Water at Room Temperature

T. Nishikata, B. H. Lipshutz

J. Am. Chem. Soc. 131, 12103 Article
246 2009

Aminations of Aryl Bromides in Water at Room Temperature

B H. Lipshutz, D. W. Chung, B. Rich

Adv. Syn. Catal. 351, 1717 Article
245 2009

Amination of Allylic Alcohols in Water at Room Temperature

T. Nishikata, B. H. Lipshutz

Org. Lett. 11, 2377 Article
244 2009

PQS:  A Newly Designed Platform for Micellar Catalysis. RCM Reactions in Water with Catalyst Recycling

B. H. Lipshutz, S. Ghorai

Org. Lett. 11, 705 Article
243 2009

A Convenient Preparation of Di-p-Chlorobenzyl Azodicarboxylate (DCAD) for Mitsunobu Couplings

B. H. Lipshutz, B. R. Taft, E. C. Swift

Synthesis (PSP) 332 Article
242 2009

Rediscovering Organocopper Chemistry Through CuH.  It’s All About the Ligand

B. H. Lipshutz

Synlett 509 (invited) Review
241 2009

Deprotection of Homoallyl (hAllyl) Derivatives of Phenols, Alcohols, Acids, and Amines”

B. H. Lipshutz, S. Ghorai

J. Org. Chem. 74, 2854 Article
240 2009

“Carboalumination/Ni-catalyzed couplings. A short synthesis of verticipyrone

B. H. Lipshutz, B. Amorelli 

Tetrahedron Lett. 50, 2144.  Article
239 2009

Total Synthesis of Piericidin A1.  Application of a Modified Negishi Carboalumination-Nickel-Catalyzed Cross-Coupling”

B. H. Lipshutz, B. Amorelli

J. Am. Chem. Soc. 131, 1396 Article
236 2008

Activated Alkenylboronates from Acetylenic Esters via CuH-Catalyzed 1,2-Addition/Transmetalation

B. H. Lipshutz, Z. V. Boskovic, D. H. Aue

Angew. Chem. Int. Ed. 47, 10183 Article
235 2008

Micellar Catalysis of Suzuki-Miyaura Cross-Couplings with Heteroaromatics in Water

B. H. Lipshutz, A. R. Abela

Org. Lett. 10, 5329 Article
234 2008

Copper + Nickel-in-Charcoal (Cu-Ni/C):  A Bimetallic, Heterogeneous Catalyst for Cross-Couplings

B. H. Lipshutz, D. M. Nihan, E. Vinogradova, B. R. Taft, Z. V. Boskovic

Org. Lett. 10, 4279 Article
233 2008

Nonracemic Diarylmethanols From CuH-Catalyzed Hydrosilylation of Diaryl Ketones

C-T. Lee, B. H. Lipshutz

Org. Lett. 10, 4187 Article
232 2008

Sonogashira Couplings of Aryl Bromides:  Room Temperature, Water Only, No Copper

B. H. Lipshutz, D. W. Chung, B. Rich

Org. Lett. 10, 3793 Article
231 2008

Transition Metal Catalyzed Cross-Couplings Going Green:  in Water at Room Temperature

B. H. Lipshutz, S. Ghorai

Aldrichimica Acta, 41, 59. Review
230 2008

CuH-Catalyzed Reactions

C. Deutsch, B. H. Lipshutz, N. Krause

Chemical Reviews 108, 2916 Review
229 2008

Tandem olefin metathesis-elimination reactions.  A new route to doubly unsaturated carbonyl derivatives

B. H. Lipshutz, S. Ghorai, Z. V. Boskovic

Tetrahedron 64, 6949 (invited) Article
228 2008

Ring-closing Metathesis at Room Temperature within Nanometer Micelles Using Water as the Only Solvent

B. H. Lipshutz, S. Ghorai, G. Aguinaldo

Adv. Syn. Catal. 350, 953 Article
227 2008

C-C Bond Formation Catalyzed Heterogeneously by Nickel-on-Graphite (Ni/Cg)

B. H. Lipshutz, T. Butler, E. Swift

Org. Lett. 10, 697 Article
226 2008

Room Temperature Suzuki-Miyaura Couplings in Water Facilitated by Nonionic Amphiphiles

B. H. Lipshutz, T. B. Petersen, A. Abela

Org. Lett. 10, 1333 Article
225 2008

Heck Couplings at Room Temperature in Nanometer Aqueous Micelles

B. H. Lipshutz, B. R. Taft

Org. Lett, 10, 1329 Article
224 2008

Olefin Cross-Metathesis Reactions at Room Temperature Using the Nonionic Amphiphile “PTS”; Just Add Water

B. H. Lipshutz, G. T. Aguinaldo, S. Ghorai, K. Voigtritter

Org. Lett. 10, 1325 Article
223 2008

(BDP)CuH: A “Hot” Stryker’s Reagent for Use in Achiral Conjugate Reductions

B. A. Baker, Z. V. Boskovic, B. H. Lipshutz

Org. Lett. 10, 289 Article
222 2008

Heterogeneous catalysis with nickel-on-graphite

B. H. Lipshutz, T. Butler, E. Swift

Org. Biomol. Chem. 6, 19 Review

 

 

Reducing the cost of making drugs for low/limited-income countries by going green

Lipshutz, B. H.