The Lipshutz group is focused on research in several areas of synthetic organic chemistry. These include a heavy emphasis on green chemistry, where the goal is to devise new technologies aimed at getting organic solvents out of organic reactions.

More traditional methodologies are also under development, in many cases involving transition metal-catalyzed processes. Total syntheses are ongoing as well, with an accent on axially chiral, naturally occurring and physiologically active biaryls.

We invite you to explore our web site to learn more about our programs.

Recent News

High school students synthesized anticancer drug, sonidegib...

Read our "Behind the paper" post on the Nature Research Community blog and learn more about our recently published article "Bridging the gap between transition metal and bio-catalysis via aqueous micellar catalysis". 

Recent Publications

"Fe-catalyzed reductive couplings of terminal (hetero)aryl alkenes and alkyl halides under aqueous micellar conditions"

Pang, H., Wang, Y., Gallou, F., Lipshutz, B. H. J. Am. Chem. Soc. 2019 Accepted

"Sustainable ppm Level Palladium-Catalyzed Aminations in Nanoreactors Under Mild, Aqueous Conditions"

Zhang, Y., Takale, B. S., Gallou, F., Reilly, J., Lipshutz, B. H. Chem. Sci. 2019, Accepted

"Atroposelective Total Synthesis of the Fourfold ortho-Substituted Naphthyltetrahydroisoquinoline Biaryl O,N-Dimethylhamatine"

Slack, E. D., Seupel, R., Aue, D. H., Bringmann, G., and Lipshutz, B. H. Chem. Eur. J. 2019, Accepted 

"A new, substituted palladacycle for ppm level Pd-catalyzed Suzuki-Miyaura cross couplings in water"

Takale, B. S., Thakore, R. R., Handa, S., Gallou, F., Reilly, J. and Lipshutz, B. H. Chem. Sci. 2019, Accepted

"Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis"

Cortes-Clerget, M.; Akporji, N.; Zhou, J.; Gao, F.; Guo, P.; Parmentier, M.; Gallou, F.; Berthon, J-Y.; Lipshutz, B. H. Nat. Comm. 2019, 10, 2169.

 

 

 

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