The Lipshutz group is focused on research associated with synthetic organic chemistry with a heavy emphasis on green chemistry. The goals include development of new technologies aimed at (1) getting organic solvents out of organic reactions, using minimum amounts of recyclable water as the reaction medium; (2) reducing the need for endangered metal catalysts, especially Pd, to ppm levels, and (3) enabling reactions to be run under very mild conditions (i.e., between rt and 45 °C) thereby minimizing by-product formation and maximizing overall efficiencies; (4) designing new ligand systems for use in organometallic chemistry, the synthesis of which is green and can be accomplished in a single step (e.g., P3N ligands: see Chem. Sci. 2025, 16, 13316)

We invite you to explore our web site to learn more about our programs in environmentally responsible synthetic chemistry.

Recent Publications

Modernizing the 12 Principles of Green Chemistry: It's Time

Lipshutz, B. H.; Handa, S.

 

Enhancing Rates of Suzuki-Miyaura Couplings of non-PFAS Fluorosulfates in Water via an Oxidative Addition Complex

Lammert, R. M.; E.; Oceguera, E. N.; and Lipshutz, B. H.

 

Special Issue on Advances in Catalysis in Aqueous Media

Papadogianakis, G.; Sheldon, R. A.; Lipshutz, B. H.; Dyson, P. J.

 
A Green Chemistry Approach to the Synthesis of an Emerging Drug for the Treatment of Celiac Disease

Nelson, C. B.; Yirak, J. R.; Baumann, M.; Freiberg, K. M.; and Lipshutz, B. H.

 
Short and Sustainable Synthesis of the Anticancer Agent Tepotinib

Boeira, E.; Moro, A.V.; and Lipshutz, B. H.

 
Comparisons of Cross-Couplings Catalyzed by Palladium vs. Earth-Abundant Metals
 
Lipshutz, B. H.
 
 

More Publications