The Lipshutz group is focused on research associated with synthetic organic chemistry with a heavy emphasis on green chemistry. The goals include development of new technologies aimed at (1) getting organic solvents out of organic reactions, using minimum amounts of recyclable water as the reaction medium; (2) reducing the need for endangered metal catalysts, especially Pd, to ppm levels, and (3) enabling reactions to be run under very mild conditions (i.e., between rt and 45 °C) thereby minimizing by-product formation and maximizing overall efficiencies; (4) designing new ligand systems for use in organometallic chemistry, the synthesis of which is green and can be accomplished in a single step (e.g., P3N ligands: see Chem. Sci. 2025, 16, 13316)

We invite you to explore our web site to learn more about our programs in environmentally responsible synthetic chemistry.

Recent Publications

Sustainable Pd-catalyzed Aminations "on Dirty Water" (2026)

Oftadeh, E; Ortiz, M.; Dismuke Rodriguez, K.; Yang, J.; Lipshutz, B. H.

 

Metal-free Aerobic Alcohol Oxidations Under Aqueous Micellar Catalysis Conditions (2026)

Mamo, K.; Buchs, E.; Jin, G.; Oftadeh, E.; Gremaud, L.; Lipshutz, B. H. 

 

In Search of the Perfect Conditions for Suzuki-Miyaura Cross-Couplings (2026)

Lipshutz, B. H.; Oftadeh, E.; Ortiz, M.

 

A Sustainable and Potentially Cost Effective Approach to the Antimalarial Drug KAF156 (ganaplacide) (2026)

Lammert, R. M.; Iyer, K. S.; Yirak, J. R.; Lipshutz, B. H.

 

Enhancing Rates of Suzuki-Miyaura Couplings of non-PFAS Fluorosulfates in Water via an Oxidative Addition Complex (2026)

Lammert, R. M.; Oceguera, E. N.; Lipshutz, B. H. 

 

 

 
 

More Publications