The Lipshutz group is focused on research associated with synthetic organic chemistry with a heavy emphasis on green chemistry. The goals include development of new technologies aimed at (1) getting organic solvents out of organic reactions, using minimum amounts of recyclable water as the reaction medium; (2) reducing the need for endangered metal catalysts, especially Pd, to ppm levels, and (3) enabling reactions to be run under very mild conditions (i.e., between rt and 45 °C) thereby minimizing by-product formation and maximizing overall efficiencies; (4) designing new ligand systems for use in organometalic chemistry. The synthesis of which is green and acomplished in a single step.

We invite you to explore our web site to learn more about our programs in environmentally responsible synthetic chemistry.

Recent Publications

Nature-Inspired Ligand Design for Pd-Catalyzed Cross Couplings in Water
 
Oftadeh, E.; Baumann, M.; Ortiz, M.; Mamo, K.; Boeira, E.; Oceguera, E. N.; Lopez-Lemus, M. S.; Fang, S.; Aue, D. H.; and Lipshutz, B. H.

 

Recent Green and Sustainable Pd-Catalyzed Aminations
 
Saunders, J. M.; Dismuke Rodriguez, K. B.; Lammert, R. M.; Yirak, J. R.; Iyer, K. S.; Wong, M. J.; and Lipshutz, B. H.
 
 
Flow-to-Flow Technology: Amide Formation in the Absence of Traditional Coupling Reagents using DPDTC

Saunders, J. M.; Oceguera, E. N.; Li, J.; Wong, M. J.; Freiberg, K. M.; and Lipshutz, B. H.

 

Nickel-Catalyzed Hydro- and Deutero-dehalogenations of (Hetero)Aryl Halides under Aqueous Micellar Catalysis Conditions

Lopez-Lemus, M. S.; Kavthe, R. D.; Thomas, R. M.; Baumann, M.; Iyer, K. S.; and Lipshutz, B. H.

More Publications