The Lipshutz group is focused on research associated with synthetic organic chemistry with a heavy emphasis on green chemistry. The goals include development of new technologies aimed at (1) getting organic solvents out of organic reactions, using minimum amounts of recyclable water as the reaction medium; (2) reducing the need for endangered metal catalysts, especially Pd, to ppm levels, and (3) enabling reactions to be run under very mild conditions (i.e., between rt and 45 °C) thereby minimizing by-product formation and maximizing overall efficiencies; (4) designing new ligand systems for use in organometallic chemistry, the synthesis of which is green and can be accomplished in a single step (e.g., P3N ligands: see Chem. Sci. 2025, 16, 13316)

We invite you to explore our web site to learn more about our programs in environmentally responsible synthetic chemistry.

Recent Publications

A Sustainable and Potentially Cost Effective Approach to the Antimalarial Drug KAF156 (ganaplacide)

Lammert, R. M.; Iyer, K. S.; Yirak, J. R.; and Lipshutz, B. H.

 

Enhancing Rates of Suzuki-Miyaura Couplings of non-PFAS Fluorosulfates in Water via an Oxidative Addition Complex

Lammert, R. M.; Oceguera, E. N.; and Lipshutz, B. H.

 

Modernizing the 12 Principles of Green Chemistry: It's Time

Lipshutz, B. H.; Handa, S.

 

Enhancing Rates of Suzuki-Miyaura Couplings of non-PFAS Fluorosulfates in Water via an Oxidative Addition Complex

Lammert, R. M.; E.; Oceguera, E. N.; and Lipshutz, B. H.

 

 

 
 

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